Tee Protein-Tyrosine Kinase Is Involved in Interleukin-3 Signaling Pathway

نویسندگان

  • Hiroyuki Mano
  • Yoshihiro Yamashita
  • Ken Sato
  • Yoshio Yazaki
چکیده

Among cytoplasmic protein-tyrosine kinases (PTKs) Tec now forms a novel subfamily with recently identified Tec-related PTKs (Btk and ltk/Tsk). Tec is known to be abundantly expressed in myeloid cells, and multiple forms of Tec protein can be generated via the mechanism of alternative splicing. In this report, we have inveatigated 5“terminal diversity of the tec messages to demonstrate a predominant form of the Tec protein in mouse hematopoietic cell lines. Using anti-

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تاریخ انتشار 2000